Funded Research 2006
The ISPB is proud to be able to continue funding research seed grants
this year, up to $5,000 each, for studies relating to the prevention of
blindness. For 2006, requests for submission of Grant Proposals were sent
out to all Departments of Ophthalmology at major institutions
and other interested parties.
Grant Requests Funded in 2006
University of Illinois at Chicago
Principal Investigator: Paul A. Knepper, M.D., Ph.D.
“PRIMARY OPEN-ANGLE GLAUCOMA AS AFFECTED BY HYPOPHOSPHORYLATED
SOLUBLE CD44.”
Principal Investigator: Lisa M. Nijm,, M.D., J.D.
Co-investigator: Lawrence J. Ulanski, II, Randal 3. Peterson, Richard
Fiscella
“USING THE STAAR COLLAMER INTRAOCULAR LENS AS A DRUG DELIVERY
SYSTEM IN THE PREVENTION OF ENDOPHTHALMITIS.”
Principal Investigator: Deepak Shukia, Ph.D. and Vaibhav Tiwari, Ph.D.
“IDENTIFYING HERPES SIMPLEX VIRUS TYP-1 RECEPTOR(S) CRUCIAL FOR VIRAL
ENTRY INTO CULTURED HUMAN CORNEAL FIBROBLASTS.”
Principal Investigator: 3m-Hong Chang, Ph.D. and Dimitri T. Azar, M.D.
“FUNCTIONAL CHARACTERIZATION OF PEPTIDE DOMAIN OF MMP-7 DERIVED
PROTEOLYTIC FRAGMENT OF COLLAGEN XVIII IN VITRO AND IN VIVO.”
Principal Investigator: Debra A. Goldstein, M.D.
“ULCERATIVE COUTIS-SPECIFIC pANCA ANTIBODIES IN THE SERA OF PATIENTS
WITH IDIOPATHIC OCULAR INFLAMMATION AND A FAMILY HISTORY OF INFLAMMATORY
BOWEL DISEASE.”
Loyola University Chicago
Principal Investigator: William Park, M.D.
“IMPACT OF MECHANICAL RUBBING ON THE EFFECTIVENESS OF NO-RUB CONTACT
LENS SOLUTION PROTEIN REMOVAL: AN TN VIVO STUDY.”
Principal Investigator: Emily Velotta, M.D.
“SEVERITY OF OCULAR COMPLICATIONS AS AN INDEPENDENT PREDICTOR OF
MORBiDITY AND MORTALITY IN TOXIC EPIDERMAL NECROLYSIS.”
Principal Investigator: Johann Ohly, M.D.
“THE EFFECT OF PAN RETINAL PHOTOCOAGULATION FOR PROLIFERATIVE DIABETIC
RETINOPATHY ON RETINAL NERVE FIBER LAYER THICKNESS.”
The University of Chicago
Principal Investigator: Stephen Roth, M.D.
“PROTEIN KINASE B (Akt) SUBTYPES AND ISCHEMIC TOLERANCE IN THE RETINA.”
Principal Investigator: Kasra Rezaei, M.D.
“AGE RELATED MACULAR DEGENERATION- WHETHER OTHER WAVELENGTHS OF LIGHT
CAN CAUSE APOPTOSIS IN RPE CELLS AND WHETHER THEY CAN PRODUCE ROS TO
DAMAGE DNA OR NOT.”
Rush University Medical Center
Principal Investigator: Bruce I Gaynes, O.D., PharmD
“THE EFFECT OF TOPICAL NERVE GROWTH FACTOR ON CORNEAL SENSITIVITY, TEAR
FLOW, EPITHELIAL HEALING RATE AND CORNEAL BIO VIABILITY IN THE MAMMALIAN
EYE SUBSEQUENT TO EXPERIMENTAL DIABETES MELLITUS.”
Department of Veterans’ Affairs-North Chicago Illinois
Principal Investigator: Evan Stubbs, Jr.,Ph.D., Jay Penman, M.D.,
Ph.D.
“STATIN-DEPENDANT REGULATION OF ENDOTHELIAL NITRIC OXIDE SYNTHASE IN
CULTURED TRAVECULAR MESHWORK CELLS.”
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